Psoriasis is a genetically determined, persistent proliferative skin disease with impredictable development. It usually begins to appear in early adulthood but at any age, it can affect patients. The manifestation, the disease may remain restricted to some areas, or may become widespread.Have a look at Psoriasis Treatment Near Me to get more info on this.
The lesions are scaly, characterized by red plaques with silvery and thick scales that easily detach and can sometimes build up on the patient’s clothes or bed. Classically they are symmetrically distributed among the bony prominences, such as the elbows and knees. But they can also affect intergluteal region of the trunk, scalp, and nails.
There is a psoriasis healing agent and existing therapies only suppress the illness as it is administered. Therefore, the therapy target is to reduce the underlying inflammation and proliferation of the epidermis. The drugs are: anti-inflammatory agents with topical hormones, topical tar and anthralin formulations, ultra-violet light UVA or UVB, and lastly, preventive medication of antimetabolite agents such as methotrexate or retinoids such as etretinate.
UVB phototherapy is already well established as a good form of treatment, but it takes approximately 25 to 30 sections to produce a skin whitening. It is known that the use of UVA and UVB causes a rapid remission of psoriasis, but the limiting factor of this therapy is the most sensitive skin that is not affected by the disease, which can be damaged by the high rays. Furthermore, there are capable of discharging units rays with high power, selectively to the plates psoriticas. In 1977 he released a paper on the use by Bonis and colleagues of the Excimer Laser for the diagnosis of psoriasis that indicated the effectiveness of this procedure. The Excimer Laser potentially has the same biological impact as UVB, but its administration is performed directly on the pad, selectively. Nevertheless, more tests are required to establish the dosage sufficient to trigger a relief of the psoritica lesions.
A group of American researchers (Departments of Dermatology and Medicine, Massachusetts General Hospital, Harvard Medical School, Boston), led by Dr. Pravit Asawanonda, conducted a study to determine the appropriate dose of the excimer laser, used selectively in the direction of each plate, and establish the efficacy and duration of remission. .
The researchers recruited adults with stabilized plaque psoriasis (plaques that have been present for more than eight weeks without alterations in their suffering). Patients were asked to use topical therapy to discontinue treatment for at least two weeks, as patients using photo-UVB therapy were recommended to suspend treatment for those on systemic therapy for four weeks and eight weeks. It excluded patients who were pregnant or breastfeeding, and patients with a history of photosensitivity or keloid formation.
In each patient four similar boards were selected. Each of these plaques received one, two, four and twenty treatment sessions, respectively. Through session of three-day period was conducted twice a week. Total time for treatment is 10 weeks.
Any patients got low intensity beam sessions, medium intensity with some and heavy intensity beam sessions with some. During the procedure, clinical assessment was performed two, four and six weeks following completion and 2 to 4 months at the conclusion of the therapy.